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Serotonin is the neurotransmitter primarily involved in mood regulation. It plays a crucial role in influencing mood, emotion, and overall emotional well-being. Research has shown that low levels of serotonin are often associated with mood disorders such as depression and anxiety. The modulation of serotonin in the brain can affect a person's mood significantly, which is why many antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs), aim to increase serotonin levels to help alleviate depressive symptoms.
Dopamine, while also relevant to mood and reward pathways, is more closely linked to pleasure, motivation, and reward-seeking behavior rather than direct mood regulation. GABA is the primary inhibitory neurotransmitter in the brain and is more associated with reducing anxiety and promoting relaxation rather than regulating mood specifically. Acetylcholine, on the other hand, is involved in various functions including memory and muscle activation but does not have a major role in mood regulation. Thus, serotonin stands out as the most significant neurotransmitter for mood management.